Acute hepatitis A, B and C but not D is still prevalent in Mongolia: a time trend analysis
نویسندگان
چکیده
BACKGROUND/AIMS Mongolia has one of the highest hepatitis A, C, B and D infection incidences worldwide. We sought to investigate changes in the proportion of acute viral hepatitis types in Mongolia over the last decade. METHODS The cohort comprised 546 consecutive patients clinically diagnosed with acute viral hepatitis from January 2012 to December 2014 in Ulaanbaatar Hospital, Mongolia. A time trend analysis investigating the change in proportion of acute hepatitis A virus, hepatitis C virus (HCV), hepatitis B virus (HBV) and hepatitis delta virus (HDV) infection among the cohort with respect to a previous published study was undertaken. RESULTS Acute hepatitis A, B and C was diagnosed in 50.9%, 26.2% and 6.0% of the cohort. Notably, 16.8% of the cohort had a dual infection. The etiologies of acute viral hepatitis were varied by age groups. The most common cause of acute viral hepatitis among 2-19 year olds was hepatitis A, HBV and superinfection with HDV among 20-40 year olds, and HCV among 40-49 year olds. Patients with more than one hepatitis virus infection were significantly older, more likely to be male and had a higher prevalence of all risk factors for disease acquisition. These patients also had more severe liver disease at presentation compared to those with mono-infection. CONCLUSIONS Acute viral hepatitis is still prevalent in Mongolia. Thus, the need for proper infection control is increasing in this country.
منابع مشابه
هپاتیت B قابل پیشگیری و درمان است
Viral hepatitis is one of five infectional factors cause early death in all over the world. Every day at least one million people die because of viral hepatitis. Six hepatitis viruses have been known until now. They are A, B, C, D, E, G, and it is probable that at least two other kinds i.e. F, and H, will be known soon. Only hepatitis B is a DNA virus, and the others are RNA viruses. All viruse...
متن کاملEpidemiology of Viral Hepatitis and Liver Diseases in Mongolia
Mongolia which is located in Northern Asia between Russia and China is endowed with one of lowest population density in the world. Acute hepatitis due all types of hepatitis virus has been reported in Mongolia. Also, dual and triple hepatitis viruses, HBV, HDV and HCV are highly prevalent among patients with chronic liver disease living in Mongolia. Due to these facts, liver cancer is the leadi...
متن کاملDetermination of Hepatitis B Virus Genotypes in Yazd, Central Province of Iran
Background and Aims: Hepatitis B virus (HBV) infects the liver and causes acute and chronic hepatitis, hepatocellular carcinoma and cirrhosis. HBV has been divided to eight genotypes (A–H) and subgenotypes of A, B, C and F. For the first time, we determined HBV genotypes in infected samples by INNO-LiPA method in Yazd, central province of Iran. Materials and Methods: This study was performed...
متن کاملبررسی شیوع و تعیین ژنوتایپ ویروس هپاتیت دلتا در بیماران HBs Ag مثبت مراجعهکننده به کلینیک تخصصی بعثت کرمان طی سالهای 92-1391
Introduction: Hepatitis D virus (HDV) is a 35 nm in diameter agent that depends on hepatitis B surface antigen in order to proliferate and accumulate. Infection with delta agent can occur spontaneously with hepatitis B virus infection and it cause acute hepatitis or develop as secondary infection in the patients with hepatitis B. Hepatitis D virus (HDV) has several genotypes based on genome seq...
متن کاملبررسی تأثیر عفونت هپاتیت ویروسی B و C بر بقای کلیه پیوندی در بیماران دریافتکننده کلیه
Background and Aim: Chronic liver disease and its complications are major problems in renal transplant recipients. Hepatitis B and C virus infections are currently the main causes of chronic liver disease in this group, and these may affect allograft outcome. Whether hepatitis B and C virus infections after renal transplantation adversely affect graft and patient survival, remains controver...
متن کامل